Neuronal Tsc1/2 complex controls autophagy through AMPK-dependent regulation of ULK1

Tuberous sclerosis complex (TSC) is a disorder arising from mutation in the TSC1 or TSC2 gene, characterized by the development of hamartomas in various organs and neurological manifestations including epilepsy, intellectual disability and autism. TSC1/2 protein complex negatively regulates the mamm...

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Detalhes bibliográficos
Main Authors: Di Nardo, Alessia, Wertz, Mary H., Kwiatkowski, Erica, Tsai, Peter T., Leech, Jarrett D., Greene-Colozzi, Emily, Goto, June, Dilsiz, Pelin, Talos, Delia M., Clish, Clary B., Kwiatkowski, David J., Sahin, Mustafa
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4065158/
https://ncbi.nlm.nih.gov/pubmed/24599401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddu101
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