Reduced surface expression and binding of fibronectin by thrombin-stimulated thrombasthenic platelets.

Thrombin stimulation results in increased surface expression of endogeneous fibronectin and binding of plasma fibronectin to human platelets. Platelets of patients with Glanzmann's thrombasthenia, a bleeding disorder, exhibit reduced thrombin-induced platelet aggregation, little or no clot retr...

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Main Authors: Ginsberg, M H, Forsyth, J, Lightsey, A, Chediak, J, Plow, E F
Format: Artigo
Jezik:Inglês
Izdano: 1983
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC436911/
https://ncbi.nlm.nih.gov/pubmed/6826726
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