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Reduced surface expression and binding of fibronectin by thrombin-stimulated thrombasthenic platelets.

Thrombin stimulation results in increased surface expression of endogeneous fibronectin and binding of plasma fibronectin to human platelets. Platelets of patients with Glanzmann's thrombasthenia, a bleeding disorder, exhibit reduced thrombin-induced platelet aggregation, little or no clot retractio...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Principais autores: Ginsberg, M H, Forsyth, J, Lightsey, A, Chediak, J, Plow, E F
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1983
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC436911/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6826726/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI110808
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