Sepsis Induces Specific Changes in Histone Modification Patterns in Human Monocytes

BACKGROUND: Sepsis is a global burden and the primary cause of death in intensive care units worldwide. The pathophysiological changes induced by the host’s systemic inflammatory response to infection are not yet fully understood. During sepsis, the immune system is confronted with a variety of fact...

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Veröffentlicht in:PLoS One
Hauptverfasser: Weiterer, Sebastian, Uhle, Florian, Lichtenstern, Christoph, Siegler, Benedikt H., Bhuju, Sabin, Jarek, Michael, Bartkuhn, Marek, Weigand, Markus A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4368631/
https://ncbi.nlm.nih.gov/pubmed/25793379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0121748
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