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Impact of human sepsis on CCCTC-binding factor associated monocyte transcriptional response of Major Histocompatibility Complex II components

BACKGROUND: Antigen presentation on monocyte surface to T-cells by Major Histocompatibility Complex, Class II (MHC-II) molecules is fundamental for pathogen recognition and efficient host response. Accordingly, loss of Major Histocompatibility Complex, Class II, DR (HLA-DR) surface expression indica...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Siegler, Benedikt Hermann, Uhle, Florian, Lichtenstern, Christoph, Arens, Christoph, Bartkuhn, Marek, Weigand, Markus Alexander, Weiterer, Sebastian
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6136812/
https://ncbi.nlm.nih.gov/pubmed/30212590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0204168
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