Postoperative abdominal sepsis induces selective and persistent changes in CTCF binding within the MHC-II region of human monocytes

BACKGROUND: Postoperative abdominal infections belong to the most common triggers of sepsis and septic shock in intensive care units worldwide. While monocytes play a central role in mediating the initial host response to infections, sepsis-induced immune dysregulation is characterized by a defectiv...

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Publicado no:PLoS One
Main Authors: Siegler, Benedikt Hermann, Altvater, Marc, Thon, Jan Niklas, Neuhaus, Christopher, Arens, Christoph, Uhle, Florian, Lichtenstern, Christoph, Weigand, Markus Alexander, Weiterer, Sebastian
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8092803/
https://ncbi.nlm.nih.gov/pubmed/33939725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0250818
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