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Protein Dynamics Associated with Failed and Rescued Learning in the Ts65Dn Mouse Model of Down Syndrome

Down syndrome (DS) is caused by an extra copy of human chromosome 21 (Hsa21). Although it is the most common genetic cause of intellectual disability (ID), there are, as yet, no effective pharmacotherapies. The Ts65Dn mouse model of DS is trisomic for orthologs of ∼55% of Hsa21 classical protein cod...

詳細記述

保存先:
書誌詳細
出版年:PLoS One
主要な著者: Ahmed, Md. Mahiuddin, Dhanasekaran, A. Ranjitha, Block, Aaron, Tong, Suhong, Costa, Alberto C. S., Stasko, Melissa, Gardiner, Katheleen J.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4368539/
https://ncbi.nlm.nih.gov/pubmed/25793384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0119491
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