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Defining the role of Porphyromonas gingivalis peptidylarginine deiminase (PPAD) in rheumatoid arthritis through the study of PPAD biology
BACKGROUND: Antibodies to citrullinated proteins (ACPAs) are a hallmark of rheumatoid arthritis (RA). Porphyromonas gingivalis peptidylarginine deiminase (PPAD) has been implicated in the initiation of RA by generating citrullinated neoantigens and due to its ability to autocitrullinate. OBJECTIVES:...
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| Publicado no: | Ann Rheum Dis |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4368502/ https://ncbi.nlm.nih.gov/pubmed/24864075 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/annrheumdis-2014-205385 |
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