A Unified Nomenclature and Amino Acid Numbering for Human PTEN

The tumor suppressor PTEN is a major brake for cell transformation, mainly due to its phosphatidylinositol 3,4,5-trisphosphate [PI(3,4,5)P(3)] phosphatase activity that directly counteracts the oncogenicity of phosphoinositide 3-kinase (PI3K). PTEN mutations are frequent in tumors and in the germ li...

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Vydáno v:Sci Signal
Hlavní autoři: Pulido, Rafael, Baker, Suzanne J., Barata, Joao T., Carracedo, Arkaitz, Cid, Victor J., Chin-Sang, Ian D., Davé, Vrushank, den Hertog, Jeroen, Devreotes, Peter, Eickholt, Britta J., Eng, Charis, Furnari, Frank B., Georgescu, Maria-Magdalena, Gericke, Arne, Hopkins, Benjamin, Jiang, Xeujun, Lee, Seung-Rock, Lösche, Mathias, Malaney, Prerna, Matias-Guiu, Xavier, Molina, María, Pandolfi, Pier Paolo, Parsons, Ramon, Pinton, Paolo, Rivas, Carmen, Rocha, Rafael M., Rodríguez, Manuel S., Ross, Alonzo H., Serrano, Manuel, Stambolic, Vuk, Stiles, Bangyan, Suzuki, Akira, Tan, Seong-Seng, Tonks, Nicholas K., Trotman, Lloyd C., Wolff, Nicolas, Woscholski, Rudiger, Wu, Hong, Leslie, Nicholas R.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4367864/
https://ncbi.nlm.nih.gov/pubmed/24985344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2005560
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