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Sepsis-induced changes in amino acid transporters and leucine signaling via mTOR in skeletal muscle

The etiology for the sepsis-induced leucine (Leu) resistance has not been fully elucidated and the present study investigated various aspects of amino acid activation of the mammalian target of rapamycin (mTOR). Sepsis in adult male rats decreased basal protein synthesis in gastrocnemius, associated...

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Bibliografische gegevens
Gepubliceerd in:Amino Acids
Hoofdauteurs: Laufenberg, Lacee J., Pruznak, Anne M., Navaratnarajah, Maithili, Lang, Charles H.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4367815/
https://ncbi.nlm.nih.gov/pubmed/25218136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00726-014-1836-6
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