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mTOR signaling in skeletal muscle during sepsis and inflammation: Where does it all go wrong?

The mammalian target of rapamycin (mTOR) is an evolutionarily conserved protein kinase that exquisitely regulates protein metabolism in skeletal muscle. mTOR integrates input from amino acids, growth factors and intracellular cues to make or break muscle protein. mTOR accomplishes this task by stimu...

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Detalhes bibliográficos
Main Authors: Frost, Robert A., Lang, Charles H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3606812/
https://ncbi.nlm.nih.gov/pubmed/21487027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiol.00044.2010
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