Concordance of IHC, FISH and RT-PCR for EML4-ALK rearrangements

The echinoderm microtubule-associated protein-like 4 anaplastic lymphoma kinase (EML4-ALK) has emerged as the second most important driver oncogene in lung cancer and the first targetable fusion oncokinase to be identified in 4-6% of lung adenocarcinomas. Crizotinib, along with a diagnostic test—the...

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Bibliographic Details
Published in:Transl Lung Cancer Res
Main Authors: Teixidó, Cristina, Karachaliou, Niki, Peg, Vicente, Gimenez-Capitan, Ana, Rosell, Rafael
Format: Artigo
Language:Inglês
Published: Pioneer Bioscience Publishing Company 2014
Subjects:
Review Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4367661/
https://ncbi.nlm.nih.gov/pubmed/25806283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3978/j.issn.2218-6751.2014.02.02
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