Loading...

Positive and Negative Regulation of Vertebrate Separase by Cdk1-Cyclin B1 May Explain Why Securin Is Dispensable

Sister chromatid cohesion is established during replication by entrapment of both dsDNAs within the cohesin ring complex. It is dissolved in anaphase when separase, a giant cysteine endopeptidase, cleaves the Scc1/Rad21 subunit of cohesin, thereby triggering chromosome segregation. Separase is held...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Hellmuth, Susanne, Pöhlmann, Christopher, Brown, Andreas, Böttger, Franziska, Sprinzl, Mathias, Stemmann, Olaf
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4367298/
https://ncbi.nlm.nih.gov/pubmed/25659430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.615310
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!