載入...

Positive and Negative Regulation of Vertebrate Separase by Cdk1-Cyclin B1 May Explain Why Securin Is Dispensable

Sister chromatid cohesion is established during replication by entrapment of both dsDNAs within the cohesin ring complex. It is dissolved in anaphase when separase, a giant cysteine endopeptidase, cleaves the Scc1/Rad21 subunit of cohesin, thereby triggering chromosome segregation. Separase is held...

全面介紹

Na minha lista:
書目詳細資料
發表在:J Biol Chem
Main Authors: Hellmuth, Susanne, Pöhlmann, Christopher, Brown, Andreas, Böttger, Franziska, Sprinzl, Mathias, Stemmann, Olaf
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2015
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4367298/
https://ncbi.nlm.nih.gov/pubmed/25659430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.615310
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!