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Structurally Distinct Ligands Rescue Biogenesis Defects of the K(ATP) Channel Complex via a Converging Mechanism
Small molecules that correct protein misfolding and misprocessing defects offer a potential therapy for numerous human diseases. However, mechanisms underlying pharmacological correction of such defects, especially in heteromeric complexes with structurally diverse constituent proteins, are not well...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4367296/ https://ncbi.nlm.nih.gov/pubmed/25637631 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.634576 |
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