RNA Polymerase III Regulates Cytosolic RNA:DNA Hybrids and Intracellular MicroRNA Expression

RNA:DNA hybrids form in the nuclei and mitochondria of cells as transcription-induced R-loops or G-quadruplexes, but exist only in the cytosol of virus-infected cells. Little is known about the existence of RNA:DNA hybrids in the cytosol of virus-free cells, in particular cancer or transformed cells...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Koo, Christine Xing'er, Kobiyama, Kouji, Shen, Yu J., LeBert, Nina, Ahmad, Shandar, Khatoo, Muznah, Aoshi, Taiki, Gasser, Stephan, Ishii, Ken J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4367256/
https://ncbi.nlm.nih.gov/pubmed/25623070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.636365
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