Oncovirus Kaposi Sarcoma Herpesvirus (KSHV) Represses Tumor Suppressor PDLIM2 to Persistently Activate Nuclear Factor κB (NF-κB) and STAT3 Transcription Factors for Tumorigenesis and Tumor Maintenance

Kaposi sarcoma herpesvirus (KSHV) is the most common cause of malignancies among AIDS patients. However, how KSHV induces tumorigenesis remains largely unknown. Here, we demonstrate that one important mechanism underlying the tumorigenesis of KSHV is through transcriptional repression of the tumor s...

Full description

Saved in:
Bibliographic Details
Published in:J Biol Chem
Main Authors: Sun, Fan, Xiao, Yadong, Qu, Zhaoxia
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2015
Subjects:
Reports
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4367247/
https://ncbi.nlm.nih.gov/pubmed/25681443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C115.637918
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items