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Coding mutations in SORL1 and Alzheimer’s disease

IMPORTANCE: Common single nucleotide polymorphisms in the SORL1 gene have been associated with late onset Alzheimer’s disease (LOAD) but causal variants have not been fully characterized nor has the mechanism been established. OBJECTIVE: To identify functional SORL1 mutations in patients with LOAD....

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Detalhes bibliográficos
Publicado no:Ann Neurol
Main Authors: Vardarajan, Badri N., Zhang, Yalun, Lee, Joseph H., Cheng, Rong, Bohm, Christopher, Ghani, Mahdi, Reitz, Christiane, Reyes-Dumeyer, Dolly, Shen, Yufeng, Rogaeva, Ekaterina, St George-Hyslop, Peter, Mayeux, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4367199/
https://ncbi.nlm.nih.gov/pubmed/25382023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.24305
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