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Coding mutations in SORL1 and Alzheimer’s disease

IMPORTANCE: Common single nucleotide polymorphisms in the SORL1 gene have been associated with late onset Alzheimer’s disease (LOAD) but causal variants have not been fully characterized nor has the mechanism been established. OBJECTIVE: To identify functional SORL1 mutations in patients with LOAD....

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Dades bibliogràfiques
Publicat a:Ann Neurol
Autors principals: Vardarajan, Badri N., Zhang, Yalun, Lee, Joseph H., Cheng, Rong, Bohm, Christopher, Ghani, Mahdi, Reitz, Christiane, Reyes-Dumeyer, Dolly, Shen, Yufeng, Rogaeva, Ekaterina, St George-Hyslop, Peter, Mayeux, Richard
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4367199/
https://ncbi.nlm.nih.gov/pubmed/25382023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.24305
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