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Myelin basic protein binds to and inhibits the fibrillar assembly of Aβ42 in-vitro()
The deposition of amyloid β-protein (Aβ) fibrils into plaques within the brain parenchyma and along cerebral blood vessels is a hallmark of Alzheimer’s disease. Aβ peptides are produced through the successive cleavage of the Aβ precursor protein by β and γ-secretase, producing peptides of between 39...
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| Publicado no: | Biochemistry |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4367193/ https://ncbi.nlm.nih.gov/pubmed/19385666 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi900037s |
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