DNA hypermethylation analysis in sputum for the diagnosis of lung cancer: training validation set approach

BACKGROUND: Lung cancer has the highest mortality of all cancers. The aim of this study was to examine DNA hypermethylation in sputum and validate its diagnostic accuracy for lung cancer. METHODS: DNA hypermethylation of RASSF1A, APC, cytoglobin, 3OST2, PRDM14, FAM19A4 and PHACTR3 was analysed in sp...

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Bibliografische gegevens
Gepubliceerd in:Br J Cancer
Hoofdauteurs: Hubers, A J, Heideman, D A M, Burgers, S A, Herder, G J M, Sterk, P J, Rhodius, R J, Smit, H J, Krouwels, F, Welling, A, Witte, B I, Duin, S, Koning, R, Comans, E F I, Steenbergen, R D M, Postmus, P E, Meijer, G A, Snijders, P J F, Smit, E F, Thunnissen, E
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2015
Onderwerpen:
Molecular Diagnostics
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4366885/
https://ncbi.nlm.nih.gov/pubmed/25719833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2014.636
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