A Fast, Sensitive and Accurate High Resolution Melting (HRM) Technology-Based Assay to Screen for Common K-ras Mutations

Background: Increasing evidence points to a negative correlation between K-ras mutations and patient’s response to, or survival benefit after, treatment with EGFR-inhibitors. Therefore, rapid and reliable assays for mutational analysis of the K-ras gene are strongly needed. Methods: We designed a hi...

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Detalhes bibliográficos
Publicado no:Cell Oncol
Main Authors: Kramer, D., Thunnissen, F. B., Gallegos-Ruiz, M. I., Smit, E. F., Postmus, P. E., Meijer, C. J. L. M., Snijders, P.J.F., Heideman, D. A. M.
Formato: Artigo
Idioma:Inglês
Publicado em: IOS Press 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4618824/
https://ncbi.nlm.nih.gov/pubmed/19478384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/CLO-2009-0466
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