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Prolonged Proinflammatory Cytokine Production in Monocytes Modulated by Interleukin 10 After Influenza Vaccination in Older Adults

We evaluated in vivo innate immune responses in monocyte populations from 67 young (aged 21–30 years) and older (aged ≥65 years) adults before and after influenza vaccination. CD14(+)CD16(+) inflammatory monocytes were induced after vaccination in both young and older adults. In classical CD14(+)CD1...

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Veröffentlicht in:J Infect Dis
Hauptverfasser: Mohanty, Subhasis, Joshi, Samit R., Ueda, Ikuyo, Wilson, Jean, Blevins, Tamara P., Siconolfi, Barbara, Meng, Hailong, Devine, Lesley, Raddassi, Khadir, Tsang, Sui, Belshe, Robert B., Hafler, David A., Kaech, Susan M., Kleinstein, Steven H., Trentalange, Mark, Allore, Heather G., Shaw, Albert C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4366602/
https://ncbi.nlm.nih.gov/pubmed/25367297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiu573
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