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Surrogacy marker paradox measures in meta-analytic settings
Because of the time and expense required to obtain clinical outcomes of interest, such as functional limitations or death, clinical trials often focus the effects of treatment on earlier and more easily obtained surrogate markers. Preliminary work to define surrogates focused on the fraction of a tr...
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| Publicado no: | Biostatistics |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4366594/ https://ncbi.nlm.nih.gov/pubmed/25236906 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/biostatistics/kxu043 |
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