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Surrogacy Assessment Using Principal Stratification With Multivariate Normal and Gaussian Copula Models
BACKGROUND: The validation of intermediate markers as surrogate markers (S) for the true outcome of interest (T) in clinical trials offers the possibility for trials to be run more quickly and cheaply by using the surrogate endpoint in place of the true endpoint. PURPOSE: Working within a principal...
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| Veröffentlicht in: | Clin Trials |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4768476/ https://ncbi.nlm.nih.gov/pubmed/25490988 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1740774514561046 |
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