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Surrogacy Assessment Using Principal Stratification and a Gaussian Copula Model
In clinical trials, a surrogate outcome (S) can be measured before the outcome of interest (T) and may provide early information regarding the treatment (Z) effect on T. Many methods of surrogacy validation rely on models for the conditional distribution of T given Z and S. However, S is a post-rand...
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Publicado no: | Stat Methods Med Res |
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Main Authors: | , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4272338/ https://ncbi.nlm.nih.gov/pubmed/24947559 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0962280214539655 |
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