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Causal assessment of surrogacy in a meta-analysis of colorectal cancer trials

When the true end points (T) are difficult or costly to measure, surrogate markers (S) are often collected in clinical trials to help predict the effect of the treatment (Z). There is great interest in understanding the relationship among S, T, and Z. A principal stratification (PS) framework has be...

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Main Authors: Li, Yun, Taylor, Jeremy M.G., Elliott, Michael R., Sargent, Daniel J.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3114655/
https://ncbi.nlm.nih.gov/pubmed/21252079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/biostatistics/kxq082
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