Interferon-λ rs12979860 genotype and liver fibrosis in viral and non-viral chronic liver disease

Tissue fibrosis is a core pathologic process that contributes to mortality in ~45% of the population and is likely to be influenced by the host genetic architecture. Here we demonstrate, using liver disease as a model, that a single-nucleotide polymorphism (rs12979860) in the intronic region of inte...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Commun
Prif Awduron: Eslam, Mohammed, Hashem, Ahmed M., Leung, Reynold, Romero-Gomez, Manuel, Berg, Thomas, Dore, Gregory J., Chan, Henry L.K., Irving, William L., Sheridan, David, Abate, Maria L., Adams, Leon A., Mangia, Alessandra, Weltman, Martin, Bugianesi, Elisabetta, Spengler, Ulrich, Shaker, Olfat, Fischer, Janett, Mollison, Lindsay, Cheng, Wendy, Powell, Elizabeth, Nattermann, Jacob, Riordan, Stephen, McLeod, Duncan, Armstrong, Nicola J., Douglas, Mark W., Liddle, Christopher, Booth, David R., George, Jacob, Ahlenstiel, Golo
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Pub. Group 2015
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4366528/
https://ncbi.nlm.nih.gov/pubmed/25740255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7422
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