Interferon-λ rs12979860 genotype and liver fibrosis in viral and non-viral chronic liver disease

Tissue fibrosis is a core pathologic process that contributes to mortality in ~45% of the population and is likely to be influenced by the host genetic architecture. Here we demonstrate, using liver disease as a model, that a single-nucleotide polymorphism (rs12979860) in the intronic region of inte...

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Publicado no:Nat Commun
Main Authors: Eslam, Mohammed, Hashem, Ahmed M., Leung, Reynold, Romero-Gomez, Manuel, Berg, Thomas, Dore, Gregory J., Chan, Henry L.K., Irving, William L., Sheridan, David, Abate, Maria L., Adams, Leon A., Mangia, Alessandra, Weltman, Martin, Bugianesi, Elisabetta, Spengler, Ulrich, Shaker, Olfat, Fischer, Janett, Mollison, Lindsay, Cheng, Wendy, Powell, Elizabeth, Nattermann, Jacob, Riordan, Stephen, McLeod, Duncan, Armstrong, Nicola J., Douglas, Mark W., Liddle, Christopher, Booth, David R., George, Jacob, Ahlenstiel, Golo
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Pub. Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4366528/
https://ncbi.nlm.nih.gov/pubmed/25740255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7422
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