Ligand Binding to the FA3-FA4 Cleft Inhibits the Esterase-Like Activity of Human Serum Albumin

The hydrolysis of 4-nitrophenyl esters of hexanoate (NphOHe) and decanoate (NphODe) by human serum albumin (HSA) at Tyr411, located at the FA3-FA4 site, has been investigated between pH 5.8 and 9.5, at 22.0°C. Values of K (s), k (+2), and k (+2)/K (s) obtained at [HSA] ≥ 5×[NphOXx] and [NphOXx] ≥ 5×...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:PLoS One
Egile Nagusiak: Ascenzi, Paolo, Leboffe, Loris, di Masi, Alessandra, Trezza, Viviana, Fanali, Gabriella, Gioia, Magda, Coletta, Massimo, Fasano, Mauro
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2015
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4366387/
https://ncbi.nlm.nih.gov/pubmed/25790235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0120603
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak