Ibuprofen Impairs Allosterically Peroxynitrite Isomerization by Ferric Human Serum Heme-Albumin

Human serum albumin (HSA) participates in heme scavenging; in turn, heme endows HSA with myoglobin-like reactivity and spectroscopic properties. Here, the allosteric effect of ibuprofen on peroxynitrite isomerization to NO(3)(−) catalyzed by ferric human serum heme-albumin (HSA-heme-Fe(III)) is repo...

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Autores principales: Ascenzi, Paolo, di Masi, Alessandra, Coletta, Massimo, Ciaccio, Chiara, Fanali, Gabriella, Nicoletti, Francesco P., Smulevich, Giulietta, Fasano, Mauro
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2009
Materias:
Enzyme Catalysis and Regulation
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2781501/
https://ncbi.nlm.nih.gov/pubmed/19734142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.010736
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