Reciprocal Allosteric Modulation of Carbon Monoxide and Warfarin Binding to Ferrous Human Serum Heme-Albumin

Human serum albumin (HSA), the most abundant protein in human plasma, could be considered as a prototypic monomeric allosteric protein, since the ligand-dependent conformational adaptability of HSA spreads beyond the immediate proximity of the binding site(s). As a matter of fact, HSA is a major tra...

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Detalhes bibliográficos
Main Authors: Bocedi, Alessio, De Sanctis, Giampiero, Ciaccio, Chiara, Tundo, Grazia R., Di Masi, Alessandra, Fanali, Gabriella, Nicoletti, Francesco P., Fasano, Mauro, Smulevich, Giulietta, Ascenzi, Paolo, Coletta, Massimo
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3605432/
https://ncbi.nlm.nih.gov/pubmed/23555601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0058842
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