Production of monocytic cells from bone marrow stem cells: therapeutic usage in Alzheimer’s disease

Accumulation of amyloid β (Aβ) is a major hallmark in Alzheimer’s disease (AD). Bone marrow derived monocytic cells (BMM) have been shown to reduce Aβ burden in mouse models of AD, alleviating the AD pathology. BMM have been shown to be more efficient phagocytes in AD than the endogenous brain micro...

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Détails bibliographiques
Publié dans:J Cell Mol Med
Auteurs principaux: Magga, Johanna, Savchenko, Ekaterina, Malm, Tarja, Rolova, Taisia, Pollari, Eveliina, Valonen, Piia, Lehtonen, Šárka, Jantunen, Esa, Aarnio, Jussi, Lehenkari, Petri, Koistinaho, Milla, Muona, Anu, Koistinaho, Jari
Format: Artigo
Langue:Inglês
Publié: Blackwell Publishing Ltd 2012
Sujets:
Original Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4365885/
https://ncbi.nlm.nih.gov/pubmed/21777378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2011.01390.x
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