Production of monocytic cells from bone marrow stem cells: therapeutic usage in Alzheimer’s disease

Accumulation of amyloid β (Aβ) is a major hallmark in Alzheimer’s disease (AD). Bone marrow derived monocytic cells (BMM) have been shown to reduce Aβ burden in mouse models of AD, alleviating the AD pathology. BMM have been shown to be more efficient phagocytes in AD than the endogenous brain micro...

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Bibliographic Details
Published in:J Cell Mol Med
Main Authors: Magga, Johanna, Savchenko, Ekaterina, Malm, Tarja, Rolova, Taisia, Pollari, Eveliina, Valonen, Piia, Lehtonen, Šárka, Jantunen, Esa, Aarnio, Jussi, Lehenkari, Petri, Koistinaho, Milla, Muona, Anu, Koistinaho, Jari
Format: Artigo
Language:Inglês
Published: Blackwell Publishing Ltd 2012
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4365885/
https://ncbi.nlm.nih.gov/pubmed/21777378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2011.01390.x
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