Ethyl Pyruvate Inhibits HMGB1 Phosphorylation and Release by Chelating Calcium

Ethyl pyruvate (EP), a simple aliphatic ester of pyruvic acid, has been shown to have antiinflammatory effects and to confer protective effects in various pathological conditions. Recently, a number of studies have reported EP inhibits high mobility group box 1 (HMGB1) secretion and suggest this mig...

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Pubblicato in:Mol Med
Autori principali: Shin, Joo-Hyun, Kim, Il-Doo, Kim, Seung-Woo, Lee, Hye-Kyung, Jin, Yinchuan, Park, Ju-Hun, Kim, Tae-Kyung, Suh, Chang-Kook, Kwak, Jiyeon, Lee, Keun-Hyeung, Han, Pyung-Lim, Lee, Ja-Kyeong
Natura: Artigo
Lingua:Inglês
Pubblicazione: ScholarOne 2015
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4365067/
https://ncbi.nlm.nih.gov/pubmed/25333921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2014.00039
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