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Ethyl Pyruvate Inhibits HMGB1 Phosphorylation and Release by Chelating Calcium
Ethyl pyruvate (EP), a simple aliphatic ester of pyruvic acid, has been shown to have antiinflammatory effects and to confer protective effects in various pathological conditions. Recently, a number of studies have reported EP inhibits high mobility group box 1 (HMGB1) secretion and suggest this mig...
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| Publicado no: | Mol Med |
|---|---|
| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
ScholarOne
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4365067/ https://ncbi.nlm.nih.gov/pubmed/25333921 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2014.00039 |
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