Anti-Inflammatory and Neuroprotective Effects of DIPOPA (N,N-Diisopropyl-2-Oxopropanamide), an Ethyl Pyruvate Bioisoster, in the Postischemic Brain

Ethyl pyruvate (EP) is a simple aliphatic ester of pyruvic acid and has been shown to have protective properties, which have been attributed to its anti-inflammatory, anti-oxidative, and anti-apoptotic functions. In an effort to develop better derivatives of EP, we previously synthesized DEOPA (N,N-...

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Vydáno v:Neurotherapeutics
Hlavní autoři: Lee, Hye-Kyung, Park, Ju-Young, Lee, Hahnbie, Kim, Il-Doo, Kim, Seung-Woo, Yoon, Sung-Hwa, Lee, Ja-Kyeong
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer International Publishing 2019
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6554410/
https://ncbi.nlm.nih.gov/pubmed/30680637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13311-019-00711-w
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