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Drug Synergy Drives Conserved Pathways to Increase Fission Yeast Lifespan

Aging occurs over time with gradual and progressive loss of physiological function. Strategies to reduce the rate of functional loss and mitigate the subsequent onset of deadly age-related diseases are being sought. We demonstrated previously that a combination of rapamycin and myriocin reduces age-...

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Veröffentlicht in:PLoS One
Hauptverfasser: Huang, Xinhe, Leggas, Markos, Dickson, Robert C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4364780/
https://ncbi.nlm.nih.gov/pubmed/25786258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0121877
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