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Down-Regulating Sphingolipid Synthesis Increases Yeast Lifespan

Knowledge of the mechanisms for regulating lifespan is advancing rapidly, but lifespan is a complex phenotype and new features are likely to be identified. Here we reveal a novel approach for regulating lifespan. Using a genetic or a pharmacological strategy to lower the rate of sphingolipid synthes...

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Detalhes bibliográficos
Main Authors: Huang, Xinhe, Liu, Jun, Dickson, Robert C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3271065/
https://ncbi.nlm.nih.gov/pubmed/22319457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002493
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