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Down-Regulating Sphingolipid Synthesis Increases Yeast Lifespan
Knowledge of the mechanisms for regulating lifespan is advancing rapidly, but lifespan is a complex phenotype and new features are likely to be identified. Here we reveal a novel approach for regulating lifespan. Using a genetic or a pharmacological strategy to lower the rate of sphingolipid synthes...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3271065/ https://ncbi.nlm.nih.gov/pubmed/22319457 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002493 |
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