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Inhibition of peroxisome fission, but not mitochondrial fission, increases yeast chronological lifespan

Mitochondria are key players in aging and cell death. It has been suggested that mitochondrial fragmentation, mediated by the Dnm1/Fis1 organelle fission machinery, stimulates aging and cell death. This was based on the observation that Saccharomyces cerevisiae Δdnm1 and Δfis1 mutants show an enhanc...

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Vydáno v:Cell Cycle
Hlavní autoři: Lefevre, Sophie D, Kumar, Sanjeev, van der Klei, Ida J
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4614869/
https://ncbi.nlm.nih.gov/pubmed/25840089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2015.1029685
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