Over-Expression of Calpastatin Inhibits Calpain Activation and Attenuates Post-Infarction Myocardial Remodeling

BACKGROUND: Calpain is activated following myocardial infarction and ablation of calpastatin (CAST), an endogenous inhibitor of calpains, promotes left ventricular remodeling after myocardial infarction (MI). The present study aimed to investigate the effect of transgenic over-expression of CAST on...

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Publicado en:PLoS One
Autores principales: Ye, Tingqiao, Wang, Qiang, Zhang, Yan, Song, Xiaofeng, Yang, Dachun, Li, De, Li, Dan, Su, Linan, Yang, Yongjian, Ma, Shuangtao
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2015
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4364764/
https://ncbi.nlm.nih.gov/pubmed/25786109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0120178
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