Upregulation of Glycolytic Enzymes, Mitochondrial Dysfunction and Increased Cytotoxicity in Glial Cells Treated with Alzheimer’s Disease Plasma

Alzheimer’s disease (AD) is a neurodegenerative disorder associated with increased oxidative stress and neuroinflammation. Markers of increased protein, lipid and nucleic acid oxidation and reduced activities of antioxidant enzymes have been reported in AD plasma. Amyloid plaques in the AD brain eli...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Jayasena, Tharusha, Poljak, Anne, Braidy, Nady, Smythe, George, Raftery, Mark, Hill, Mark, Brodaty, Henry, Trollor, Julian, Kochan, Nicole, Sachdev, Perminder
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4364672/
https://ncbi.nlm.nih.gov/pubmed/25785936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0116092
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