Role of Nicotinamide Adenine Dinucleotide and Related Precursors as Therapeutic Targets for Age-Related Degenerative Diseases: Rationale, Biochemistry, Pharmacokinetics, and Outcomes

Significance: Nicotinamide adenine dinucleotide (NAD(+)) is an essential pyridine nucleotide that serves as an essential cofactor and substrate for a number of critical cellular processes involved in oxidative phosphorylation and ATP production, DNA repair, epigenetically modulated gene expression,...

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Bibliographische Detailangaben
Veröffentlicht in:Antioxid Redox Signal
Hauptverfasser: Braidy, Nady, Berg, Jade, Clement, James, Khorshidi, Fatemeh, Poljak, Anne, Jayasena, Tharusha, Grant, Ross, Sachdev, Perminder
Format: Artigo
Sprache:Inglês
Veröffentlicht: Mary Ann Liebert, Inc., publishers 2019
Schlagworte:
Comprehensive Invited Review
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6277084/
https://ncbi.nlm.nih.gov/pubmed/29634344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2017.7269
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