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N(6)-FUNCTIONALIZED CONGENERS OF ADENOSINE WITH HIGH POTENCY AT A(2)-ADENOSINE RECEPTORS: POTENTIAL LIGANDS FOR AFFINITY CHROMATOGRAPHY

Adenosine analogues substituted at N(6) with spacer arms designed for attachment to soluble macromolecules or to solid supports for affinity chromatography are agonists at the A(2)–adenosine receptor that mediates coronary vasodilation in the dog. The most active analogues had spacer arms terminatin...

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Publicado en:Biochem Biophys Res Commun
Autores principales: Jacobson, Kenneth A., Yamada, Noboyiuki, Kirk, Kenneth L., Daly, John W., Olsson, R.A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 1986
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4364609/
https://ncbi.nlm.nih.gov/pubmed/3013167
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