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A Functionalized Congener Approach to Adenosine Receptor Antagonists: Amino Acid Conjugates of 1,3-Dipropylxanthine

1,3-Dipropyl-8-phenylxanthine, a synthetic analog of theophylline and a potent antagonist of adenosine at A(1) and A(2)-adenosine receptors, has been attached covalently through a functionalized chain to amino acids and oligopeptides. The xanthine conjugates have been studied as competitive inhibito...

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Detalhes bibliográficos
Main Authors: JACOBSON, KENNETH A., KIRK, KENNETH L., PADGETT, WILLIAM L., DALY, JOHN W.
Formato: Artigo
Idioma:Inglês
Publicado em: 1986
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3459325/
https://ncbi.nlm.nih.gov/pubmed/3005825
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