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The Receptor for Advanced Glycation End Products (RAGE) Contributes to the Progression of Emphysema in Mice

Several recent clinical studies have implied a role for the receptor for advanced glycation end products (RAGE) and its variants in chronic obstructive pulmonary disease (COPD). In this study we have defined a role for RAGE in the pathogenesis of emphysema in mice. RAGE deficient mice (RAGE-/-) expo...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Sambamurthy, Nisha, Leme, Adriana S., Oury, Tim D., Shapiro, Steven D.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4364508/
https://ncbi.nlm.nih.gov/pubmed/25781626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0118979
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