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The Role of the Receptor for Advanced Glycation End-Products in a Murine Model of Silicosis

BACKGROUND: The role of the receptor for advanced glycation end-products (RAGE) has been shown to differ in two different mouse models of asbestos and bleomycin induced pulmonary fibrosis. RAGE knockout (KO) mice get worse fibrosis when challenged with asbestos, whereas in the bleomycin model they a...

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Autori principali: Ramsgaard, Lasse, Englert, Judson M., Tobolewski, Jacob, Tomai, Lauren, Fattman, Cheryl L., Leme, Adriana S., Kaynar, A. Murat, Shapiro, Steven D., Enghild, Jan J., Oury, Tim D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2841632/
https://ncbi.nlm.nih.gov/pubmed/20333255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009604
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