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Activation and assembly of the inflammasomes through conserved protein domain families

Inflammasomes are oligomeric protein complexes assembled through interactions among the death domain superfamily members, in particular the CARD and PYD domains. Recent progress has shed lights on how the ASC PYD can polymerize to form filaments using multiple domain:domain interfaces, and how the c...

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Bibliografski detalji
Izdano u:Apoptosis
Glavni autori: Jin, Tengchuan, Xiao, Tsan Sam
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4364414/
https://ncbi.nlm.nih.gov/pubmed/25398536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10495-014-1053-5
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