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Activation and assembly of the inflammasomes through conserved protein domain families
Inflammasomes are oligomeric protein complexes assembled through interactions among the death domain superfamily members, in particular the CARD and PYD domains. Recent progress has shed lights on how the ASC PYD can polymerize to form filaments using multiple domain:domain interfaces, and how the c...
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| Publicado no: | Apoptosis |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4364414/ https://ncbi.nlm.nih.gov/pubmed/25398536 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10495-014-1053-5 |
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