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Activation and assembly of the inflammasomes through conserved protein domain families

Inflammasomes are oligomeric protein complexes assembled through interactions among the death domain superfamily members, in particular the CARD and PYD domains. Recent progress has shed lights on how the ASC PYD can polymerize to form filaments using multiple domain:domain interfaces, and how the c...

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Bibliografiska uppgifter
I publikationen:Apoptosis
Huvudupphovsmän: Jin, Tengchuan, Xiao, Tsan Sam
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4364414/
https://ncbi.nlm.nih.gov/pubmed/25398536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10495-014-1053-5
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